使用辅助生殖技术怀孕的新生儿的低出生体重
Bratislavske lekarske listy
|January 14, 2024
概括
辅助生殖技术 (ART) 的使用与新生儿低出生体重的风险更高有关. 与体外受精或卵细胞接收相比,冷胚胎移植的风险似乎是最低的.
科学领域:
- 生殖医学 生殖医学
- 新生儿健康 新生儿健康
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,辅助生殖技术 (ART) 的使用正在增加.
- 有关新生儿健康结果,特别是出生体重,在ART后存在担忧.
- 现有的国际研究表明,与自发怀孕相比,在ART怀孕的婴儿的出生体重较低.
研究的目的:
- 为了调查不同ART方法之间,低出生体重的风险是否有所不同.
- 确定哪种ART方法与低出生体重的最低风险有关.
- 为了比较体外受精 (IVF) 与新鲜胚胎移植,冷胚胎移植 (FET) 和卵细胞接收之间的风险.
主要方法:
- 从捷克 (2013-2018) 分析匿名的个人交付数据.
- 来自国家生殖健康登记处的数据.
- 二元物流回归用于评估风险因素,控制共变量.
主要成果:
- 与接受FET (CI 1.15-1.48) 的女性相比,接受试管婴儿治疗的女性出生体重低的风险高出30% (CI 1.15-1.48).
- 与接受FET (CI 1.17-1.97) 的女性相比,接受卵细胞接收的女性出生体重低的风险高出52%.
- 在研究的ART方法中,冷胚胎移植与低出生体重的风险最低.
结论:
- 这些发现与国际关于ART和新生儿健康结果的数据一致.
- 特定的ART方法带有低出生体重的差异性风险.
- 与新生儿IVF或新鲜卵细胞接收相比,冷胚胎移植可能是新生儿出生体重更安全的选择.
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