显著环境经验的遗产 - - 化学感应的见解
Brian G Dias1,2,3
1Developmental Neuroscience and Neurogenetics Program, The Saban Research Institute, Los Angeles, CA, United States.
Chemical senses
|January 14, 2024
概括
父母的环境在几代人之间显著塑造了后代的生物学. 这篇评论探讨了化学感知体验,如气味,如何创造传承的持久遗产,影响后代的发育和压力反应.
科学领域:
- 表观遗传学和发育生物学
- 神经生物学和行为科学 神经生物学和行为科学
背景情况:
- 越来越多的证据表明,父母的环境对后代生理学,生物学和神经生物学有深远的影响.
- 动物和昆虫模型被用来研究父母压力和营养的多代影响.
研究的目的:
- 综合当前对未来几代人继承的化学传感遗产的理解.
- 探索继承化感体验的概念,原因和后果.
- 将化学传感遗产与父母经验对后代生物学的更广泛影响联系起来.
主要方法:
- 对利用模拟生物中化学传感暴露的最新研究进行审查.
- 专注于利用突出的化学传感体验来研究代际影响的研究.
- 综合了关于父母的化学感知环境如何影响后代的研究结果.
主要成果:
- 父母接触环境体验会改变后代的大脑发育,压力激素反应和基因表达.
- 化学感知体验是理解代际影响的强大工具.
- 遗传的化学传感遗产会影响后代的生物学和压力反应.
结论:
- 父母的化学感知体验可以在后代中建立持久的遗产.
- 了解这些遗产可以了解父母对子女影响的更广泛机制.
- 这个字段告诉我们,跨世代的环境暴露如何塑造生物结果.
相关概念视频
Tactile and Chemical Senses
296
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
296
Olfaction
44.4K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
44.4K
Introduction to Special Senses
5.8K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
5.8K
Physiology of Smell and Olfactory Pathway
8.5K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
8.5K
Gustation
48.0K
Gustation is a chemical sense that, along with olfaction (smell), contributes to our perception of taste. It starts with the activation of receptors by chemical compounds (tastants) dissolved in the saliva. The saliva and filiform papillae on the tongue distribute the tastants and increase their exposure to the taste receptors.
48.0K
Olfactory Receptors: Location and Structure
9.3K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.3K


