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更新的CRUSADE评分预测医院内出血:在泰国皮肤穿透冠状动脉干预注册表中的外部验证

Ply Chichareon¹, Noppadol Chamnarnphol¹, Mann Chandavimol²

¹Cardiology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

|January 14, 2024

概括

克鲁萨德评分有效预测亚洲患者的出血风险,非ST段升高心肌梗塞 (NSTEMI) 接受皮肤穿冠状动脉干预 (PCI). 完整版和简化版在泰国人群中表现出强的表现.

科学领域:

心脏病学心脏病学
临床风险分层的临床风险分层
干预心脏病学干预心脏病学

背景情况:

推使用CRUSADE评分来预测非ST段升高心肌梗塞 (NSTEMI) 患者的住院出血风险.
需要对亚洲人群进行皮肤冠状动脉干预 (PCI) 的CRUSADE评分进行验证.

研究的目的:

验证和更新CRUSADE评分,用于预测PCI治疗的NSTEMI患者的住院大出血.
在这个患者队列中评估简化的CRUSADE得分的性能.

主要方法:

使用泰国PCI注册表的数据 (2018年5月 - 2019年8月).
根据8个预测因素计算了CRUSADE得分,并使用后勤回归来适应住院大出血.
修订和简化得分,使用C统计和校准评估绩效.

主要成果:

原来的CRUSADE评分显示出良好的预测能力 (C统计值0.817).
修订和简化的CRUSADE评分 (4个变量) 显示出出色的表现 (C统计分别为0.839和0.837).
简化得分在泰国NSTEMI群体中实现了最佳校准.

结论:

克鲁萨德风险评分,无论是完整的还是简化的形式,都非常适合预测接受PCI的泰国NSTEMI患者的出血风险.
简化的CRUSADE评分为这一群体的风险分层提供了一个实用的工具.

关键词:

在医院内出血.非ST段升高心肌梗塞心肌梗塞通过皮肤进行冠状动脉干预.更新的克鲁萨德分数 (CRUSADE score) 已经得到了更新.

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