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在跨直肠前列腺活检中对不同短期抗生素预防方案的比较

E Krsakova¹, A Cermak², M Fedorko²

¹Department of Urology, University Hospital Brno, Brno, Czechia.

The Journal of hospital infection

|January 14, 2024

概括

短期抗生素预防有效地预防了通过直肠前列腺活检 (PB) 的传染性并发症. 包括氏素,米醇和西普罗夫洛克萨在内的治疗方案显示出类似的低并发症率,氏素为诺基诺提供了可行的替代品.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
传染性疾病传染性疾病
在瘤学瘤学.

背景情况:

前列腺癌是老年男性普遍存在的恶性瘤.
跨直肠前列腺活检 (PB) 是一种常见的诊断程序.
感染性并发症可能来自PB,需要预防性策略.

研究的目的:

评估不同短期抗生素预防方案的疗效.
为了比较通过直肠前列腺活检 (PB) 后感染并发症的发生率.
评估抗生素选择,以预防活检后感染.

主要方法:

一项前性随机研究,涉及544名接受过直肠超声导向PB的患者.
患者被分配到三个抗生素预防组:氏素/氏素组合,氏素单独或氏素单独.
检查前分析了直肠拭子,并在手术后一个月监测并发症.

主要成果:

总共进行了605次PB,其中544名患者被纳入分析.
感染性并发症发生在所有组1.83%的患者 (10例) 中.
在抗生素治疗方案之间没有观察到统计学上显著的并发症率差异;没有患者需要住院治疗.

结论:

短期抗生素预防,包括氏胺和氏,是有效的减少PB后的传染性并发症.
斯福米辛米醇为诺基诺隆抗生素提供了一种适合的替代品,用于预防.
目前的抗生素治疗方案在预防严重的活检后感染方面显示出安全性和有效性.

关键词:

抗生素预防抗生素预防复杂性复杂性复杂性斯福米辛 (phosfomycin) 是一种甲胺醇的药物.通过直肠进行前列腺活检.

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