患有恶性肠道阻塞的癌症患者的营养护理途径:一项回顾性多中心研究
Pinal S Patel1, Konstantinos Fragkos2, Niamh Keane2
1Intestinal Failure Unit, University College London Hospitals, London, United Kingdom; Cambridge Centre for Intestinal Rehabilitation and Transplant, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Clinical nutrition ESPEN
|January 14, 2024
概括
对恶性肠道阻塞 (MBO) 患者来说,亲肠道营养 (PN) 的获取方式有所不同. 只有三分之一的MBO入院被转介给营养团队,在转介和非转介组之间没有观察到生存差异.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 由于恶性肠道阻塞 (MBO) 而导致肠道衰竭的患者的亲肠营养 (PN) 接入不一致.
- 在护理途径和结果存在差异,基于PN的营养团队转诊.
研究的目的:
- 对MBO患者的营养护理途径和患者结局进行检查,基于转诊到PN的营养团队.
主要方法:
- 在英国八家医院对232名成人MBO患者进行了回顾性队列研究.
- 对人口统计,营养和医疗数据的分析,比较PN的转诊 (R) 与未转诊 (NR) 患者.
- 统计分析包括Kruskal-Wallis,Chi-Squared,多级回归和Cox生存回归.
主要成果:
- 在347个MBO入院中,只有35% (123) 被转介给PN的营养团队.
- 没有转诊 (NR) 的患者年龄较大,更有可能接受保守治疗.
- 在所述 (R) 组中,多学科团队讨论和饮食接触的可能性显著增加.
- 平均入院体重减轻8%;整体存活率在R组和NR组之间没有差异.
结论:
- 在MBO患者中,转诊到营养小组是很少见的,仅发生在三分之一的入院患者中.
- 饮食审查也是不理想的,超过一半的入院涉及营养学家.
- 需要进一步的前性研究来评估这些多样化的护理途径对临床结果和生活质量的影响.
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