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相关概念视频

Psychoneuroimmunology: Diabetes and Cancer01:19

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
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相关实验视频

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Isolation of Human Islets from Partially Pancreatectomized Patients
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一项关于恶性瘤和糖尿病之间的关系的研究.

Sebiha Ozge Duman1, Merve Kayali Sevim2, Nevin Dinccag3

  • 1Istanbul University Oncology Institute, Istanbul, Turkiye.

Clinical nutrition ESPEN
|January 14, 2024
PubMed
概括

恶性病和糖尿病 (DM) 是普遍存在的健康问题. 这项研究检查了癌症患者的DM,发现一些公开的DM患者的随访不佳,癌症治疗可以诱导DM,需要定期监测葡萄糖.

关键词:
癌症 癌症 癌症 癌症糖尿病是一种糖尿病.肥胖问题 肥胖问题风险 风险 风险 风险 风险

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科学领域:

  • 在瘤学瘤学.
  • 内分泌学 在内分泌学.
  • 公共卫生 公共卫生

背景情况:

  • 恶性病和糖尿病 (DM) 代表着全球健康面临的重大挑战,其患病率不断增加,患病率/死亡率高.
  • 了解这些疾病之间的相互作用对于有效的患者管理和公共卫生策略至关重要.

研究的目的:

  • 在被诊断为恶性瘤的个体中调查明显的DM的患病率.
  • 评估诊断前血糖控制,DM持续时间和治疗对恶性瘤发育和类型的影响.
  • 评估非糖尿病癌症患者治疗后发展DM的风险.

主要方法:

  • 一组469名患有各种恶性瘤的患者 (年龄26-70岁) 被分为三个组:先前存在的/同时存在的明显的DM (I组,n=97),在抗癌治疗期间发展的DM (II组,n=17) 和非糖尿病恶性瘤患者 (III组,n=355).

主要成果:

  • 一组患者的平均BMI较高,身体活动较低. 显著比例的先前存在的DM患者没有得到足够的随访或治疗. 在癌症治疗期间患有DM的患者中,注意到胰腺手术和皮质类固醇的使用.

结论:

  • 糖尿病患者的查计划应考虑与癌症共同的风险因素.
  • 抗癌治疗可以加速DM的发展,强调在瘤治疗期间需要定期监测葡萄糖代谢.