从青春期到成年期:在前性队列研究中,地中海饮食的坚持和心脏代谢健康
Niloufar Saber1, Farshad Teymoori2, Mitra Kazemi Jahromi3
1Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|January 14, 2024
概括
青少年坚持地中海饮食得分 (MDS) 与更好的成人心脏代谢健康有关. 年轻人中MDS的较高预测了成年人中高总胆固醇和改善的腰围,禁食血糖和总胆固醇水平的风险较低.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 青少年的饮食模式越来越被认为是长期心脏代谢健康的预测因素.
- 了解特定饮食 (如地中海饮食) 在成长期的影响对于预防策略至关重要.
研究的目的:
- 调查青少年期间遵守地中海饮食得分 (MDS) 与成年期心脏代谢结果之间的关联.
- 确定青少年MDS是否预测腰围,血糖和脂质状况等风险因素的变化.
主要方法:
- 一项涉及668名青少年 (10-19岁) 的队列研究,来自德黑兰脂质和葡萄糖研究.
- 地中海饮食得分 (MDS) 通过经过验证的食物频率调查问卷进行评估;人体测量,禁食血糖 (FBG),以及在基线和随访期间 (6.8 ± 2.9年) 测量的脂质谱.
- 多变量回归模型 (线性和Cox比例危险) 用于分析MDS和心脏代谢风险因素和并发症之间的关联.
主要成果:
- 更高的青少年MDS与腰围 (WC),禁食血糖 (FBG) 和总胆固醇 (TC) 在6.8年的有利变化有显著关联.
- 在MDS的最高三分之一的个体表明,与最低三分之一 (HR=0.36) 相比,在成年后患高总胆固醇 (TC) 的风险明显较低.
- 青少年MDS与其他检查的心脏代谢风险因素之间没有发现显著的关联.
结论:
- 在青少年时期更坚持地中海式饮食,与成年后心脏代谢因素的改善有关.
- 青少年地中海饮食得分 (MDS) 可能成为预测未来心脏代谢健康的有价值指标.
- 研究结果支持在青少年中推广地中海饮食模式,以长期预防心血管疾病.
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