相关实验视频

Updated: Jul 5, 2025

Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood

Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood

Published on: February 5, 2020

在接受免疫检查点抑制剂 (ICI) 治疗的晚期黑色素瘤患者的症状体验

Natalie Jackson-Carroll¹, Constance Johnson², Hussein Tawbi³

¹Cizik School of Nursing, The University of Texas Health Science Center at Houston; Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.

Seminars in oncology nursing

|January 14, 2024

概括

接受免疫检查点抑制剂 (ICI) 治疗晚期黑色素瘤的患者经历了各种症状和对生活质量的影响. 清晰的沟通和验证的工具可以改善患者的护理和对治疗结果的理解.

科学领域:

在瘤学瘤学.
免疫治疗是一种免疫疗法.
患者报告的结果

背景情况:

免疫检查点抑制剂 (ICI) 治疗改善了晚期黑色素瘤的结果.
然而,症状负担和生活质量 (HRQoL) 影响是不可预测的.
患者在ICI治疗中的经验需要更深入的定性理解.

研究的目的:

为了探索患者在晚期黑色素瘤ICI治疗期间的症状负担和HRQoL的经验.
为了获取有关症状干扰和患者感知的定性数据.
确定患有晚期黑色素瘤和ICI治疗的患者旅程中的关键主题.

主要方法:

半结构面试的描述性探索性内容分析.
参与者 (n=19) 患有晚期黑色素瘤,正在接受ICI治疗.
利用修改的MD安德森症状清单和癌症治疗-黑色素瘤的功能评估.

主要成果:

不同类型的症状体验:痛苦 (84%),疲劳 (68%),皮肤变化 (53%),疼痛 (30%),腹 (30%).
变量HRQoL干扰情绪 (47%),人际关系 (26%) 和活动 (21%).
普遍的不确定性 (68%) 尽管积极的治疗预期 (58%).

结论:

黑色素瘤和ICI治疗的身体和情绪负担,加上结果的不确定性,是显著的.
关于诊断,预后和治疗的明确沟通至关重要.
护士可以使用经过验证的患者报告结果 (PRO) 仪器来更好地了解患者的症状经历.

关键词:

免疫治疗是一种免疫疗法.黑色素瘤是一种黑色素瘤.患者报告的结果.生活质量生活的质量.症状症状症状症状

更多相关视频

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Published on: February 8, 2018

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

相关概念视频

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...