在患有2型糖尿病的老年脆弱人群中减少可能不合适的药物的使用:集群随机对照试验 (D-MED研究) 的协议
Lauren O'Mahoney1, Patrick Highton1, Ruksar Abdala1
1Diabetes Research Centre, University of Leicester, Leicester, UK; National Institute for Health Research Applied Research Collaboration East Midlands, Leicester, UK.
Primary care diabetes
|January 14, 2024
概括
这项研究评估了一个电子系统,以减少老年患者不适当的糖尿病药物. 数字工具和培训表明,在患有2型糖尿病的脆弱个体中,药物减强有潜力.
科学领域:
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
- 医疗信息学 医疗信息学
背景情况:
- 在患有2型糖尿病 (T2D) 的老年患者中,过度处方药物可能导致诸如跌倒,骨折和死亡率增加等不良事件,特别是在脆弱的个体中.
- 目前的临床指导方针往往优先考虑药物强化,而不是老年人T2D管理的适当减强.
研究的目的:
- 评估电子决策支持系统的有效性,并结合培训,以减少T2D的老年,脆弱个体潜在不合适的药物的强化.
- 在12个月的时间里,将这项干预与"通常"护理的结果进行比较.
主要方法:
- 一个开放的标签,多站点,实用集群随机试验进行.
- 一般医生 (GP) 实践被随机分配到"增强护理"组 (接受电子决策支持系统和培训) 或对照组.
- 电子系统识别符合条件的患者药物减强,指导医疗保健专业人员通过临床算法.
主要成果:
- 研究招聘于2022年6月开始,数据收集从2023年1月开始.
- 从40个实践中提取了基线数据,涉及3145名患者.
结论:
- 数字技术,如计算机决策系统,有望减少不适当的药物使用.
- 这些系统可能会对弱势患者群体的药物减强过程有显著的帮助.
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