增强对比的超声波作为ICG淋巴图的辅助方法,用于功能性淋巴动脉静脉解
Young Woong Mo1,2, Seung Jun Lee1,2, Dong Won Lee1,2
1Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea.
Journal of surgical oncology
|January 15, 2024
概括
与绿色氨酸 (ICG) 结合的对比增强超声波 (CEUS) 通过更好地可视化深层淋巴管道来改善淋巴结 (LVA).
科学领域:
- 血管外科 血管外科
- 医疗成像医学成像
- 淋巴 edem 管理 淋巴 edem 管理
背景情况:
- 印ocyanine绿色 (ICG) 淋巴图是用于淋巴的标准,但透深度有限 (1-2厘米).
- 淋巴影响上肢和下肢,需要有效的诊断和手术干预.
- 淋巴管静脉解 (LVA) 是一种用于治疗淋巴的手术治疗方法.
研究的目的:
- 为了比较LVA的临床结果,使用对比增强超声波 (CEUS) 与ICG与ICG单独进行手术前成像.
- 评估CEUS辅助LVA在识别和向功能性淋巴管道方面的有效性.
- 评估CEUS引导的LVA对四肢体积和四肢间比率的影响.
主要方法:
- 一项前性研究,涉及接受上肢和下肢淋巴瘤LVA的患者.
- 在全身麻醉下进行皮下注射Sonazoid®,用于CEUS视觉化淋巴管道.
- 使用CEUS加ICG和仅ICG组之间的生物阻抗来比较四肢周长和四肢间比率 (ILR) 的变化.
主要成果:
- 在CEUS加ICG组和ICG-only组之间没有发现显著的人口差异.
- 在CEUS加ICG组中,在上肢 (p=0.042) 和下肢 (p=0.002) 均发现肢体间比率 (ILR) Z1值的统计学显著下降.
- CEUS成功地发现了深层,功能和大淋巴管道.
结论:
- 与ICG相结合的CEUS可以比单独使用ICG更好地识别深层淋巴血管.
- 通过CEUS辅助的LVA证明了在淋巴结胀治疗中改善功能结果的潜力.
- 这种组合成像模式可能会提高淋巴静脉解的成功率.
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