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Updated: Jul 5, 2025

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在多个祖先的参考面板中,基因型归算的准确性和次要祖先的质量指标

Mingyang Shi1, Chizu Tanikawa2, Hans Markus Munter3

  • 1Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

Briefings in bioinformatics
|January 15, 2024
PubMed
概括

基因型归算质量指标可能会高估代表性不足的人口中的准确性. 模板切换率 (θ值) 在全基因组关联研究中显著影响归算准确性和质量评估.

关键词:
东亚地区的东亚地区.一个TOPM的参考面板.基因类型的归算 基因类型的归算归算质量指标是归算质量指标.模板转换利率的模板代表性不足的人口.

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