相关实验视频
Updated: Jul 5, 2025

06:23
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
4.9K
在患有腰椎椎间盘的患者中,MRI特征在副脊柱肌肉,炎症过程和相关的背部疼痛之间的联系
Xiaolong Chen1, Peng Cui1, Yongjin Li1
1Department of Orthopaedics Xuanwu Hospital Capital Medical University Beijing China.
JOR spine
|January 15, 2024
概括
椎间盘退化 (IDD) 与侧脊椎肌肉变化和炎症有关. 这项研究发现,TNF-α等炎症标志物与肌肉脂肪透相关,并影响腰部疼痛 (LBP) 症状.
科学领域:
- 生物医学研究的研究.
- 肌肉骨科学 肌肉骨科学
- 炎症研究的研究.
背景情况:
- 椎间盘退化 (IDD) 在腰部疼痛 (LBP) 中很常见,并与脊椎肌肉结构变化有关.
- 炎症在这些肌肉变化中的作用及其与LBP的联系仍然不清楚.
研究的目的:
- 调查健康人与腰椎间盘 (LDH) 患者之间的副脊柱肌肉结构差异.
- 将LDH患者与没有LBP患者进行比较.
- 确定肌肉结构变化与炎症标志物表达之间的关系.
主要方法:
- 前性队列研究,测量肌肉横截面区域 (CSA) 和脂肪退化.
- 采购多肌 (MM) 组织,通过qPCR进行基因表达分析.
- 统计分析包括t测试,奇平方和斯皮尔曼相关性.
主要成果:
- 健康个体比LDH患者显示出较大的MM功能CSA和较少的脂肪退化.
- 与非LBP患者相比,LBP患者的MM脂肪透量增加.
- 在MM中,TNF-α水平显著更高,脂肪透率更大,与IL-1β,MM结构和临床结果相关.
结论:
- 研究结果支持这样一个假设,即IDD涉及在副脊柱肌肉中的炎症失调.
- 这种炎症失调可能会显著影响副脊髓组织健康和LBP症状.
相关概念视频
Muscles of the Vertebral Column
1.4K
The back muscles that lie deep into the thoracolumbar fascia are called intrinsic or true back muscles. These muscles are divided into four layers: superficial, intermediate, deep, and deepest layers.
Superficial Layer:
The superficial layer consists primarily of the splenius muscles, which include the splenius capitis and splenius cervicis. These muscles are mainly responsible for the head and cervical spine movements, including extension, rotation, and lateral bending. The splenius capitis...
Superficial Layer:
The superficial layer consists primarily of the splenius muscles, which include the splenius capitis and splenius cervicis. These muscles are mainly responsible for the head and cervical spine movements, including extension, rotation, and lateral bending. The splenius capitis...
1.4K
Magnetic Resonance Imaging
5.2K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.2K
General Structure of a Vertebra
2.8K
A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous...
2.8K

