在肝病患者中呼吸道病毒感染的患病率和预测因素
Jasmine Samal1, Tushar Prabhakar2, Manya Prasad2
1Department of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi, India.
呼吸道病毒感染 (RVI) 在患有流感样疾病 (ILI) 的肝病患者中很常见. 女性性别,不补偿性肝硬化和B型流感感染预测更糟糕的结果,强调了早期病毒诊断的必要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 临床病毒学 临床病毒学
背景情况:
- 呼吸道病毒感染 (RVI) 导致大量住院治疗,并可能导致不良后果,特别是在免疫受损的个体.
- 准确的RVI病因鉴定对于防止非细菌感染患者滥用抗生素至关重要.
研究的目的:
- 为了确定RVI的频谱和相关的临床特征在肝病患者呈现流感样疾病 (ILI).
主要方法:
- 从2016年9月到2022年12月,对患有ILI的肝病患者的病历进行了回顾性审查.
- 使用FilmArray 2.0呼吸道面板进行呼吸道病毒识别.
主要成果:
- 在1577名具有ILI的肝病患者中,RVI的总体患病率为28%.
- 非流感病毒 (NIV) 比流感病毒更为普遍 (73%).
- 死亡的独立风险因素包括女性性别 (OR:2.5),B型流感感染 (OR:3.3) 和不补偿性肝硬化 (OR:3.9).
- 流感的季节性发生在季风和冬季,而NIV则全年流通.
结论:
- 这项研究提供了关于ILI肝病患者RVI发病率和病毒病因分布的见解.
- 女性性别,不补偿性肝硬化和B型流感感染与不良的临床结果有显著的关联.
- 早期诊断ILI病毒病因的病因学诊断可以改善患者的管理和了解疾病流行率.
更多相关视频
07:21Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
04:11Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
Published on: December 15, 2023
相关概念视频
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
