从代谢功能障碍相关的脂肪肝疾病到代谢功能障碍相关的脂肪性肝病:争议和共识
1Department of Gastroenterology, Ruijin Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai 201801, China. drchenli@163.com.
World journal of hepatology
|January 15, 2024
概括
新的代谢功能障碍相关的脂肪性肝病 (MASLD) 命名法不同于MAFLD. 无论是MASLD还是MAFLD,都强调代谢功能障碍和正确诊断,而非侵入性测试仍然有效.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢障碍 代谢障碍 代谢障碍
- 肝脏疾病名称表 肝脏疾病名称表
背景情况:
- 2023年欧洲肝脏研究协会大会引入了新的命名:与代谢功能障碍相关的脂肪性肝病 (MASLD).
- 这是在2020年引入代谢功能障碍相关的脂肪肝疾病 (MAFLD) 之后,代表了非酒精性脂肪肝疾病的第二次重大更名.
- 无论是MASLD还是MAFLD,都承认新陈代谢功能障碍在肝硬化病的发病过程中的核心作用.
研究的目的:
- 综合比较MASLD和MAFLD命名和定义之间的差异和共识.
- 分析诊断框架,临床管理和对结果的影响的差异.
- 突出提高公众对这些疾病的认识的重要性.
主要方法:
- 对MASLD和MAFLD命名和定义进行比较的编辑分析.
- 审查现有的文献和临床指南.
- 讨论诊断方法和临床影响.
主要成果:
- 在MASLD和MAFLD框架,定义和临床管理策略之间存在重大差异.
- 发现了相当大的共识,特别是在强调正确诊断而不是负面诊断方面.
- 这两个框架都承认代谢功能障碍的关键作用和非侵入性测试的价值.
结论:
- 了解MASLD和MAFLD之间的细微差别对于准确的诊断和增强的临床实践至关重要.
- 需要进一步努力,才能在这些不断变化的肝病分类上达成更大的共识.
- 非侵入性检测仍然是诊断和管理MASLD和MAFLD的宝贵工具.
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