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在皮肤T细胞淋巴瘤中,ATF5通过PI3K/AKT/mTOR途径促进恶性T细胞的存活

Mengzhou Cao1,2,3, Pan Lai1,2,3, Xiangjun Liu1,2,3

  • 1Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China.

Frontiers in immunology
|January 15, 2024
PubMed
概括

激活转录因子5 (ATF5) 在皮肤T细胞淋巴瘤 (CTCL) 中过度表达,并促进瘤细胞的存活. 这一发现为CTCL病理学和潜在的治疗点提供了新的见解.

关键词:
癌症的发病因子 癌症的发病因子细胞内膜网膜的压力应激恶性T细胞恶性T细胞酸胺3-酶酶的作用是什么转录因子的转录因子

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