现象成像技术 (Phenomic Imaging) 是一种现象成像技术
Lizhen Lan1, Kai Feng1, Yudan Wu1
1Human Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.
Phenomics (Cham, Switzerland)
|January 15, 2024
概括
现象成像可视化跨度尺度的人类特征,与基因组学和代谢学相结合. 这种方法有助于理解复杂的生物系统,并开发新的诊断和治疗方法.
科学领域:
- 综合生物学,医学和成像技术的多学科科学.
背景情况:
- 人类现象学研究受基因,表观遗传学,器官,微生物群,饮食和环境影响的可观察到的特征.
- 现象成像可以捕获各种尺度上的解剖学,功能,代谢和生化数据,无论是体内还是体外.
研究的目的:
- 审查现象成像模式及其在人类现象学中的应用.
- 探索现象成像与其他奥米克学科的整合.
主要方法:
- 使用各种成像技术可视化和测量表型.
- 为了全面理解,将宏观和微观现象类型关联起来.
- 整合现象成像数据与基因组学,转录组学,蛋白质组学,免疫组学和代谢组学.
主要成果:
- 现象成像为正常和异常的人类特征提供了详细的视图.
- 与其他OMIC数据的整合增强了对生物系统的理解.
- 确定了新的治疗和诊断策略的潜力.
结论:
- 现象成像对于破译复杂的人类现象至关重要.
- 多式联络数据集成,包括现象成像,是推进精准医学的关键.
- 这种综合方法有望在了解健康和疾病方面取得重大突破.
相关概念视频
Genomics
36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K
Proteomics
7.3K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.3K
Positron Emission Tomography
4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K
Reporter Genes
11.3K
Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
11.3K
Imaging Studies II: Positron Emission Tomography and Scintigraphy
122
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
122


