相关实验视频

Updated: Jul 5, 2025

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

中央视网膜动脉堵塞后完全失明的发生率与眼神新血管化

Harshvardhan Chawla¹, Hayley J Redrick¹, Joshua T Pannell¹

¹Department of Ophthalmology, Louisiana State University School of Medicine, New Orleans, LA, USA.

Journal of vitreoretinal diseases

|January 15, 2024

概括

中央视网膜动脉封闭 (CRAO) 与二次眼球新血管化 (ONV) 构成完全失明的高风险. 超过一半的失明病例发生在ONV发病后4个月内,强调关键的随访遵守.

科学领域:

眼科医生眼科眼科
视网膜血管疾病视网膜血管疾病
眼科瘤学眼科瘤学

背景情况:

中央视网膜动脉堵塞 (CRAO) 可以导致严重的视力损伤.
二次眼球新血管化 (ONV) 是CRAO的一种已知的并发症.
在CRAO与ONV后完全失明的确切时间和发生率需要进一步阐明.

研究的目的:

用CRAO和二次ONV来确定基于时间的眼睛完全失明的发生率.
在这个患者队列中分析视力损失的风险因素和进展.
为临床管理和患者咨询提供有关后续遵守的信息.

主要方法:

使用电子健康记录进行回顾性队列研究.
纳入标准:CRAO后的二次ONV患者,不包括其他病因和先前治疗.
卡普兰-梅尔分析,以评估总盲的累积发病率 (没有光感知的最佳校正视力敏度).

主要成果:

在345个有CRAO的眼睛中,34个符合纳入标准;平均随访时间为22.0个月.
全盲的累积发病率在24个月后达到49.4%.
在全盲病例中,很大一部分 (53.3%) 发生在ONV发病后4个月内.

结论:

在CRAO之后的二次ONV带有进展到完全失明的重大风险.
血管新生玻璃眼可以在CRAO后长达4个月表现出来,需要延长的监测期.
眼外科手术可能有助于延迟进一步的视力丧失;持续的患者随访至关重要.

关键词:

中央视网膜动脉封闭闭塞新血管玻璃眼新血管玻璃眼.没有光感知.眼部新血管化的情况.视网膜的血管封闭完全失明完全失明

更多相关视频

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

相关概念视频

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...