化和改变对感官输入的反应性作为患有自闭症特征的成年人中出现创伤后压力症状的脆弱性因素
Liliana Dell'Osso1, Giulia Amatori1, Federico Giovannoni1
1Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
CNS spectrums
|January 15, 2024
概括
患有自闭症特征 (AT) 的人更有可能经历创伤后应激障碍 (PTSD). 特定的AT,如硬的日常生活和狭的兴趣,预测PTSD症状.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 新兴研究表明,自闭症谱系障碍 (ASD) 或自闭症特征 (ATs) 个体中创伤和创伤后应激障碍 (PTSD) 的发生率更高.
- 自闭症特征与PTSD之间的关联的确切性质仍然不完全理解.
- 需要进一步调查以澄清这种关系,并确定有助于创伤相关症状的特定自闭症维度.
研究的目的:
- 量化评估自闭症特征 (AT) 和创伤后应激障碍 (PTSD) 之间的关系.
- 确定自闭症谱系障碍 (ASD) 的哪些特定维度与创伤和与压力相关的症状最强烈相关.
- 将ASD患者的PTSD患病率和症状严重程度与健康对照人群 (HCs) 进行比较.
主要方法:
- 使用成人自闭症下值谱 (AdAS谱) 和创伤和损失谱 (TALS) 问卷进行评估.
- 包括68名被诊断患有自闭症的受试者和64名健康对照 (HC).
- 使用曼-惠特尼U测试,奇方测试,斯皮尔曼相关性和逻辑回归用于统计分析.
主要成果:
- 具有显著自闭症特征 (AT) 的个人报告了30%的PTSD率,明显高于HCs.
- 与HC相比,在AT组中观察到较高的TALS总和域分数.
- 自闭症谱系障碍 (ASD) 总分预测了PTSD的存在,不灵活,坚持例行,限制性兴趣和反领域是重要的预测因素.
结论:
- 与健康对照组 (HCs) 相比,具有显著自闭症特征 (AT) 的个人更有可能出现创伤后应激障碍 (PTSD) 症状.
- 特定的自闭症特征,包括反思维,狭的兴趣和感官反应,似乎可以预测创伤后压力症状.
- 这些发现强调了在评估和理解受影响个人的PTSD时考虑自闭症特征的重要性.
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