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Updated: Jul 5, 2025

Author Spotlight: Understanding DNA Damage Response in Mammalian Oocytes and Preimplantation Embryos
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NONO的核质拘禁屏蔽DNA双链断裂从异常的转录

Barbara Trifault1,2, Victoria Mamontova1,2, Giacomo Cossa2

  • 1Mildred Scheel Early Career Center for Cancer Research (Mildred-Scheel-Nachwuchszentrum, MSNZ) Würzburg, University Hospital Würzburg, Josef-Schneider-Strasse 2, D-97080 Würzburg, Germany.

Nucleic acids research
|January 15, 2024
PubMed
概括

对DNA损伤的反应涉及RNA结合蛋白. 这项研究揭示了一条核细胞通路,其中非POU域含有八聚体结合蛋白 (NONO) 被DNA损伤诱导的RNA与核细胞结合,帮助DNA修复.

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