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患者报告的纤维肌痛症状的影响 (PRISM-FM)

Jennifer Weinstein¹, Spencer Rosero², Jamison Seabury²

¹J. Weinstein, MS, S. Rosero, BS, J. Seabury, BS, A. Varma, BS, C. Engebrecht, BS, S. Khosa, MBBS, Center for Health + Technology, Rochester, New York; jennifer.weinstein@chet.rochester.edu.

The Journal of rheumatology

|January 15, 2024

概括

纤维肌痛 (FM) 症状如疼痛,疲劳和睡眠问题显著影响日常生活. 疾病负担与残疾状况和就业变化有关.

科学领域:

类风湿病学类风湿病学
症状研究症状研究
患者报告的结果

背景情况:

纤维肌痛 (FM) 是一种复杂的慢性疼痛疾病.
了解全方位的 FM 症状及其影响对于患者护理至关重要.
现有的研究往往侧重于诊断标准,可能会忽视更广泛的症状负担.

研究的目的:

确定成年人纤维肌痛 (FM) 症状的频率和相对重要性.
确定与 FM 患者疾病负担较高相关的因素.
探索人口统计/残疾因素与症状患病率之间的关系.

主要方法:

与15名FM参与者进行半结构面试.
对1085名FM参与者进行了一项国际横截面研究.
评估了149个主题中的149个症状的流行程度和重要性,并对影响因素进行了子组分析.

主要成果:

患病率最高的症状:疼痛 (99.8%),肌肉疼痛 (99.8%),疲劳 (99.3%).
对生活的影响最大:疲劳 (2.88),疼痛 (2.85),肌肉敏感 (2.79),睡眠问题 (2.70).
症状患病率与修改的兰金表,残疾状况和就业变化有很强的关联.

结论:

纤维肌痛患者经历了超出传统诊断标准的多样化,改变生活的症状.
疲劳,睡眠障碍和活动限制是很大的负担.
根据人口统计和残疾状况,在FM子组中,症状的患病率有所不同.

关键词:

这就是PRISM.疾病负担疾病负担纤维肌痛是一种纤维肌痛.患者报告的结果.

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