人类诺罗病毒与肠道微生物群/微生物之间的相互作用:范围审查
Yaqi Yang1, Ran An1, Chenang Lyu1
1Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Food microbiology
|January 15, 2024
概括
人类诺罗病毒 (HuNoV) 与肠道微生物相互作用,影响感染和症状. 微生物可以促进或抑制HuNoV,这取决于它们的特定特征,为预防策略提供了潜力.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 病毒学 病毒学
背景情况:
- 人类诺罗病毒 (HuNoV) 导致严重的食物传播疾病和急性胃肠炎.
- 越来越多地认识到HuNoV与肠道微生物群之间的相互作用,但了解得很少.
- 这种相互作用的机制和宿主影响需要进行系统的调查.
研究的目的:
- 系统地审查HuNoV与肠道微生物群之间的相互作用.
- 探索这种相互作用对HuNoV感染和相关症状的影响.
主要方法:
- 对HuNoV和肠道微生物群相互作用的现有研究进行范围审查.
主要成果:
- HuNoV可以与肠道微生物结合,改变微生物的组成,多样性和基因表达.
- 肠道微生物对HuNoV感染性表现出双重影响,可以促进或抑制复制.
- 矛盾的微生物效应部分归因于基因组抗原和其他微生物物质的差异.
结论:
- 了解HuNoV与微生物群的相互作用对于破译感染动态至关重要.
- 特定的微生物特征影响宿主对HuNoV. HuNoV. 的反应.
- 这些发现可以指导微生物的选择,以预防或减轻HuNoV症状.
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