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Updated: Jul 5, 2025

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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ZBTB7B是一种通过抑制c-Jun表达和功能来抑制肝细胞癌发病的容许性调节剂

Yue Zhu1, Qinqin Wang2, Xinyu Xie1

  • 1State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.

Cell death & disease
|January 15, 2024
PubMed
概括

转录因子ZBTB7B在肝癌发病时起作用作为瘤抑制剂. 它的缺失通过重新激活胎儿基因程序并促进c-Jun信号传递,加速肝细胞癌 (HCC).

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