营养状况不佳与老年人奥米克朗感染的严重程度有关
Xiaohan Gu1, Yongchao Guo1, Yongmei Shi2,3
1Department of Clinical Nutrition, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
BMC infectious diseases
|January 15, 2024
概括
老年人营养状况不佳显著增加了中度至重度的新冠肺炎2019 (COVID-19) 感染Omicron的风险. 保持良好的营养对于老年COVID-19患者的更好的结果至关重要.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 营养科学 营养科学
背景情况:
- COVID-19的Omicron变种在全球占主导地位.
- 关于老年COVID-19患者的营养状况的研究有限.
- 这项研究通过检查老年人的营养状况和Omicron严重程度来解决这一差距.
研究的目的:
- 确定感染Omicron变种的老年患者营养状况不佳的发生率.
- 为了探索营养状况和这个人口群体中Omicron感染的严重程度之间的关系.
- 确定与严重感染风险增加相关的因素.
主要方法:
- 追溯的横截面研究设计.
- 根据症状,患者被分为轻度和中度至重度的组.
- 迷你营养评估简单表格 (MNA-SF) 用于评估营养状况 (得分0-11表示营养不良).
- 进行了炎症标志物 (NLR,PLR,SII) 的计算和比较.
主要成果:
- 分析了324名老年患者 (平均年龄73岁);54.3%的营养状况不佳.
- 营养不良与年龄较大,疫苗接种率较低,并发病率较高以及炎症标志物 (NLR,PLR,SII) 较高有关.
- 较高的MNA-SF得分与中度至重度感染的几率比率降低相关 (aOR 0.852,P=0.034).
结论:
- 营养状况不佳是老年人中适度至严重的Omicron感染的重要危险因素.
- 营养状况是老年人COVID-19严重程度的独立预测因素.
- 改善营养状况的干预措施可能会减轻老年COVID-19患者的严重结果.
相关概念视频
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
COPD: Pathogenesis and Clinical Features
275
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
275
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
334
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
334
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Pneumonia III: Complications and Assessment
227
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
227


