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登革热病毒检测的创新:传统和电化学生物传感器方法的概述

Shadan Raza¹, Renu Poria¹, Deepak Kala²

¹Department of Bio-Sciences and Technology, Maharishi Markandeshwar (Deemed to Be) University, Mullana, Ambala, India.

Biotechnology and applied biochemistry

|January 16, 2024

概括

早期检测登革热病毒至关重要. 本次审查涵盖了传统方法和新型电化学生物传感器,强调了CRISPR/Cas集成,以更快,更准确的登革热诊断.

科学领域:

病毒学病毒学
生物医学工程生物医学工程
分析化学分析化学

背景情况:

病毒性传染病构成了重大的全球威胁,登革热病毒 (DENV) 是常见的感染原因.
登革热表现出各种症状,从轻度发烧到严重的登革热出血性发烧,早期诊断仍然是一个挑战.
现有的诊断方法在及时和准确检测DENV.往往面临局限性.

研究的目的:

审查和总结登革热病毒检测方法的进展.
探索用于早期登革热识别的电化学生物传感器的设计和制造.
评估生物识别分子和新兴技术如CRISPR/Cas在DENV传感中的重要性.

主要方法:

关于常规诊断技术 (基于核酸,PCR,血清学) 的综合文献综述.
详细检查用于DENV检测的电化学生物传感器设计和制造.
在生物感知中分析生物识别元素 (乳酸,核酸,抗体) 和CRISPR/Cas系统.

主要成果:

电化学生物传感器为快速和灵敏的DENV检测提供了传统方法的有希望的替代方案.
各种生物识别分子和CRISPR/Cas等先进技术可以提高生物传感器的性能.
该审查强调了电化学方法在及时诊断登革热方面的优势.

结论:

电化学生物传感器在早期检测登革热病毒方面取得了重大进展.
整合新技术和优化生物识别策略可以进一步提高诊断能力.
本次审查强调了电化学传感在应对及时登革热诊断的全球挑战方面的潜力.

关键词:

生物感应平台的生物感应平台.登革热:登革热是指登革热的一种疾病.登革热检测检测器登革热检测器电化学生物传感器纳米材料的使用方法护理点系统的系统.

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