维生素A介导的出生缺陷:叙述性审查
Raegan B Abadie1, Abigail A Staples1, Lillian V Lauck1
1School of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Cureus
|January 16, 2024
概括
怀孕期间母亲的维生素A摄入量需要仔细监测. 缺乏和过多的维生素A都会导致胎儿的异常,强调需要均衡的营养和规范的补充.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 发育毒理学 发展毒理学
背景情况:
- 母亲的维生素A状况显著影响胎儿的发育.
- 怀孕期间的维生素A缺乏 (VAD) 和过量都会带来产性风险.
- 不规范的多种维生素使用导致发达国家过度摄入维生素A.
研究的目的:
- 为了强调怀孕期间监测维生素A水平的关键重要性.
- 为了告知与VAD和维生素A过量相关的产性风险.
- 强调需要均衡的孕产妇营养和规范的补充剂.
主要方法:
- 关于怀孕期间维生素A代谢现有文献的综述.
- 对全球不同地区的VAD和过量疫情数据的分析.
- 关于与母亲维生素A状况相关的胎儿结果信息的综合.
主要成果:
- 维生素A缺乏与夜盲,骨异常和上皮细胞问题有关.
- 怀孕期间过度摄入维生素A可以导致胎儿中枢神经系统变形.
- 不平等存在,在发展中国家普遍存在VAD,在发达国家则过剩.
结论:
- 孕妇必须保持推的维生素A剂量,避免缺乏和过量.
- 教育和对维生素A补充剂的监管对于预防胎儿产性至关重要.
- 适当管理母亲的维生素A摄入量可以减轻胎儿发育的风险.
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