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Updated: Jul 5, 2025

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在RTK/RAS途径向治疗的获得性耐药性的现场建模

Nancy E Sealover1, Patricia T Theard1, Jacob M Hughes1

  • 1Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

iScience
|January 16, 2024
PubMed
概括

通过抑制SHP2信号传递,可以延迟获得的对癌症疗法的耐药性,如奥西默蒂尼布. 这种方法使耐药细胞重新敏感,并为抗癌基因驱动癌症的组合疗法提供了一个新的框架.

关键词:
生物化学 生物化学生物化学方法 生物化学方法癌症 癌症 癌症 癌症细胞生物学 细胞生物学

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