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Updated: Jul 5, 2025

Enabling Real-Time Compensation in Fast Photochemical Oxidations of Proteins for the Determination of Protein Topography Changes
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Enabling Real-Time Compensation in Fast Photochemical Oxidations of Proteins for the Determination of Protein Topography Changes

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同位素枯竭增加了FPOP的空间分辨率上下质谱分析分析

Marek Polák1,2, Jiří Černý3, Petr Novák1,2

  • 1Institute of Microbiology of the Czech Academy of Sciences, 14220 Prague, Czech Republic.

Analytical chemistry
|January 16, 2024
PubMed
概括

同位素耗尽的蛋白质显著改善了蛋白质快速光化学氧化 (FPOP) 实验的上下质谱 (MS) 分析中的信号噪声比. 这种方法增强了蛋白质结构和相互作用分析,揭示了更多的氧化位点和修饰.

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