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在髓状细胞中表达的孤儿G蛋白结合受体141作为炎症抑制剂起作用

Atsuya Sawabe1, Shogo Okazaki2, Akira Nakamura1

  • 1Division of Immunology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, 1-15-1, Fukumuro, Sendai 983-8536, Japan.

Journal of leukocyte biology
|January 16, 2024
PubMed
概括

G蛋白结合受体141 (GPR141) 抑制免疫反应. 缺乏GPR141的小鼠表现出恶化的实验性自身免疫脑膜炎,这表明GPR141针对慢性炎症性疾病.

关键词:
在G蛋白结合受体141中.自身免疫性疾病是一种自身免疫性疾病.树突细胞是一种树突细胞.实验性的自身免疫性脑膜炎.单细胞 (Monocytes) 是一种单细胞.骨髓状细胞是骨髓状细胞.

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