恒星性质块用于治疗COVID-19后的帕罗斯米亚
Bita R Naimi1, Emily Garvey1, Megha Chandna1
1Department of Otolaryngology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
International forum of allergy & rhinology
|January 16, 2024
概括
恒星性质块 (SGB) 可能改善COVID后嗅觉功能障碍患者的呼吸量和生活质量. 然而,SGB在本研究中并没有显著改善气味识别得分.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
背景情况:
- 后COVID嗅觉功能障碍 (OD) 和帕洛斯米亚可能与dysautonomia和交感过敏反应有关.
- 恒星节阻断 (SGB) 是一种潜在的干预措施,可以调节这些自主反应.
研究的目的:
- 评估SGB作为COVID后嗅觉功能障碍治疗的疗效.
- 评估SGB对帕洛斯米亚严重程度,气味识别和生活质量的影响.
主要方法:
- 47名COVID后OD患者的回顾性和前性病例系列,接受单边或双边SGB.
- 患者完成了简短的气味识别测试 (BSIT) 和评估症严重程度和生活质量的调查.
- 在不同SGB队列中比较了治疗前和治疗后的得分.
主要成果:
- 在任何一个队列中,SGB并没有显著改善臭味识别的BSIT分数.
- 在SGB治疗后,帕洛斯米亚的严重程度显著下降 (p < 0.001).
- 与食物享受,饭菜准备和社交相关的帕洛斯米亚触发因素的数量和生活质量显著改善 (p < 0.05).
结论:
- 在COVID后的OD患者中,SGB可能为主观和生活质量提供好处.
- SGB对客观气味识别的影响需要进一步调查.
- 需要使用安慰剂控制的研究来证实这些发现.
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