谁会转向第三线治疗过度活跃的膀? 来自AQUA注册表的趋势
Dora Jericevic1, Katherine Shapiro1, Max Bowman2
1Department of Urology, New York University Langone, New York, New York.
Urology practice
|January 16, 2024
概括
很少有过度活跃的膀患者转向BTX-A等第三线疗法,进展时间超过一年. 年龄,性别和保险等因素会影响这种OAB治疗途径.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 临床医学 临床医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 过度活性膀 (OAB) 管理通常涉及连续治疗.
- 第三线治疗方法 (皮肤穿神经刺激,神圣神经调节,本质毒素A膀注射 [BTX-A]) 是耐火性OAB的选择.
- 了解影响第三线治疗进展的因素对于优化患者护理至关重要.
研究的目的:
- 确定与从二线到三线OAB治疗的进展相关的患者和提供者因素.
- 为了确定进展到第三线OAB治疗的中位时间.
- 分析第三线OAB疗法的使用模式.
主要方法:
- 对2014-2020年AUA质量注册表数据的分析.
- 包括接受二线治疗的具有异常性OAB的成年患者.
- 多变量分析评估影响第三线治疗进展的因素.
主要成果:
- 只有1.2%的符合条件的患者进展到第三线OAB治疗.
- 年龄较大 (65-79岁),女性性别,白人种族和政府保险与更高的进展率有关.
- 无胺毒素A注射在膀 (BTX-A) 是最常见的第三线疗法;进展的中位时间为15.4个月.
结论:
- 第三线OAB治疗的实施是罕见的和延迟的,进展超过一年.
- 人口统计和保险因素显著影响到第三线OAB治疗的可能性.
- 有潜在的需要提高适合OAB患者的第三线治疗的可访问性和利用性.
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