种族是否会影响儿童的骨健康指数? 一个试点研究研究
Grammatina Boitsios1, Thomas Saliba2, Maria Pilar Aparisi Gómez3
1Paediatric Imaging Department, Queen Fabiola Children's Hospital (HUDERF), Université Libre de Bruxelles, Avenue Jean Joseph Crocq 15, 1020, Brussels, Belgium. gboitsios@gmail.com.
Pediatric radiology
|January 16, 2024
概括
骨健康指数 (BHI) 是评估儿童骨矿物质含量的可靠工具,在不同种族中显示出比埃克斯顿-史密斯指数 (ESI) 更低的变化. BHI提供基于性别和种族的具体趋势,有助于检测异常的骨密度.
科学领域:
- 儿科放射学 儿科放射学
- 骨矿物代谢 骨矿物代谢
- 定量放射学是一种量化放射学.
背景情况:
- 病理状况可以改变儿童成长期间的骨矿物质含量.
- 骨矿物质含量可以从骨年龄评估中估计,没有额外的成本或辐射.
- 目前的方法,如埃克斯顿-史密斯指数 (ESI) 和BoneXpert®的骨健康指数 (BHI),在不同种族群体中缺乏验证.
研究的目的:
- 在欧洲居住的健康的欧洲高加索和北非儿童中建立ESI和BHI的规范值.
- 为了比较这些族群之间的ESI和BHI的变化和趋势.
主要方法:
- 追溯分析了434名儿童 (3-15岁) 的手和手腕放射图.
- 使用BoneXpert®软件进行自动BHI计算.
- 盲目放射科医生的手动ESI计算.
- 使用中位数百分比的标准偏差来比较方法的可变性.
主要成果:
- 与欧洲高加索人相比,北非儿童的BHI较低 (P < 0.001).
- 显著比例的儿童 (13.6%的女孩,15.5%的男孩) 患有BHI比平均水平高出2 SD以上.
- ESI表现出比BHI更高的变化,特别是在8-12岁的欧洲女孩中.
- 在所有年龄和种族群体中,BHI的变化率低于15%.
结论:
- BHI是识别异常骨矿物质含量儿童的可靠工具.
- 与ESI相比,BHI显示出较低的变化和明显的性别和种族特异性趋势.
- BHI的可靠性支持其在不同的儿科群体中用于骨健康评估.
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