阻塞性睡眠呼吸暂停的儿童的中央和混合呼吸暂停:腺切除术的影响
Joselina Antunes1, João Carvalho2, Carolina Marinho2
1Otorhinolaryngology, Head and Neck Surgery Department, Professor Doutor Fernando Fonseca Hospital, IC19, 2720-276, Amadora, Portugal. Joselina.antunes@hff.min-saude.pt.
概括
腺切除术显著改善了中度至重度阻塞性睡眠呼吸暂停综合征 (OSAS) 的儿童的混合性呼吸暂停指数 (MAI) 和中央呼吸暂停指数 (CAI). 这种手术使大多数受影响儿童的非阻塞性呼吸暂停正常化.
科学领域:
- 儿科睡眠医学 儿科睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 儿童的阻塞性睡眠呼吸暂停综合征 (OSAS) 经常出现混合性和中央性呼吸暂停.
- 在儿科OSAS中经常观察到非阻塞性呼吸暂停,影响治疗策略.
研究的目的:
- 调查腺切除术对混合呼吸暂停指数 (MAI) 和中央呼吸暂停指数 (CAI) 的影响.
- 评估腺切除术在患有中度至重度OSAS和非阻塞性呼吸暂停症的儿童中的有效性.
主要方法:
- 对80名患有中度至重度OSAS的儿童的多睡眠学数据的回顾性分析.
- 包括没有并发症,接受腺切除术的儿童.
主要成果:
- 腺切除术导致MAI (1.2至0.5) 和CAI (1.0至0.5) 的显著降低.
- 手术后,91.7%的儿童表现为正常化的MAI,75.6%的儿童表现为正常化的CAI.
- 该研究包括80名儿童 (55名男孩,25名女孩),平均年龄为3.6岁.
结论:
- 腺切除术有效地减少了中度至重度OSAS儿童的阻塞性和非阻塞性呼吸暂停.
- 该程序显示了MAI和CAI的显著改善,这表明它对中央和混合呼吸暂停有好处.
相关概念视频
01:21Sleep Apnea
157
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
157
01:30Tonsillitis I: Introduction
263
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
263
01:23Chronic Pharyngitis
2.2K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
2.2K
01:29Suctioning the Nasopharyngeal Airway
423
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
423
01:26Tonsillitis II: Management
114
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
114
01:28Adrenergic Agonists: Mixed-Action Agents
717
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
717