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Updated: Jul 5, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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无活化TREX1释放癌细胞的STING-干扰素信号,并促进抗瘤免疫力

Tetsuo Tani1, Haritha Mathsyaraja2, Marco Campisi1

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

Cancer discovery
|January 16, 2024
PubMed
概括

在癌细胞中禁用TREX1酶释放STING-IFN信号,增强抗瘤免疫力. 这种方法通过增强免疫性来使瘤对免疫检查点封锁和细胞疗法敏感.

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