子周长作为心血管疾病死亡率的额外预测指标:在中国东北部进行的一项多中心前性基于人口的研究
Guangxiao Li1, Han Yan2, Li Jing2
1Department of Medical Record Management Center, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Preventive medicine
|January 16, 2024
概括
子周长 (NC) 和子与身高的比 (NHR) 在预测心血管疾病 (CVD) 死亡率方面表现有前途. 较高的NC和NHR值与中国人口中心血管疾病死亡风险增加有关.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 人类测量学 人类测量学.
背景情况:
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 识别心血管疾病死亡率的可访问和可靠的预测因素对于预防策略至关重要.
- 子周长 (NC) 和子与身高的比 (NHR) 是简单的人类测量指标,可能反映中心脂肪和相关的健康风险.
研究的目的:
- 评估子周长 (NC) 和子与身高比 (NHR) 对未来心血管疾病 (CVD) 死亡率的预测能力.
- 在一般人群中评估NC和NHR与整体心血管疾病死亡率,中风死亡率和冠心病 (CHD) 死亡率的关联.
- 在已建立的心血管疾病风险模型中确定NC和NHR的增量预测值.
主要方法:
- 一项多中心前性研究,涉及来自中国东北部的18796名参与者.
- 多变量考克斯回归模型用于分析NC/NHR和心血管疾病死亡结果之间的关联.
- 进行了重新分类分析,以量化NC和NHR的预测附加值.
主要成果:
- 更高的子周长 (NC) 独立地与整体心血管疾病死亡率 (HR 1.83) 和冠心病 (CHD) 死亡率 (HR 2.40) 的风险增加有关.
- 增加的NC与较高的缺血性中风死亡风险有关,但不是出血性中风.
- 将NC或NHR添加到现有模型中,使得整体心血管疾病死亡率的正确分类分别提高了12.1%和16.3%.
结论:
- 子周长 (NC) 和子与高度的比 (NHR) 是潜在的,易于测量的心血管疾病 (CVD) 死亡率的预测指标.
- 较高的NC和NHR值与心血管疾病死亡率的风险更高有关.
- 这些人体测量措施可能会增强现有的心血管疾病风险评估工具.
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