[胆囊切除术作为十二指肠胃反流的危险因素]
Edgard Chávez-Mendoza1, Victor Parra-Pérez2
1Universidad Nacional Mayor de San Marcos. Lima, Perú; Servicio de Gastroenterología, Hospital San José del Callao. Lima, Perú.
概括
胆囊切除术显著增加了十二指肠胃反流 (DGR) 的风险,这是胆汁流回胃的情况. 50岁以上的年龄也是DGR的危险因素.
科学领域:
- 胃肠病学 胃肠病学
- 消化系统健康 消化系统健康
- 外科手术的结果
背景情况:
- 十二指肠胃反流 (DGR) 涉及胆汁流回胃,可能导致粘膜损伤和增加癌症风险.
- 胆囊切除术,切除胆囊,是一种常见的手术程序,可能会产生胃肠道副作用.
研究的目的:
- 为了确定经过胆囊切除术的患者中初级DGR的患病率.
- 调查胆囊切除术是否是导致DGR发展的危险因素.
主要方法:
- 进行了一项观察性,分析性横截面研究.
- 分析了408名在秘鲁利马接受上消化器内镜检查的患者.
- 根据内镜检查结果,患者被分为DGR和非DGR组.
主要成果:
- DGR的总体患病率为25.74%,但在有胆囊切除病史的患者中,患病率上升至52.11%.
- 患有胆囊切除术病史的患者患上DGR的几率高出2.58倍 (p<0.001).
- 50岁或以上的年龄也被确定为DGR的危险因素 (p=0.025).
结论:
- 胆囊切除术是发展初级十二指肠胃反流的重要危险因素.
- 随着年龄的增长,DGR的风险也会增加.
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