退行性神经认知障碍和创伤性脑损伤中的自杀率
Tiina Talaslahti1, Milena Ginters1, Anniina Palm1
1Department of Psychiatry, University of Helsinki, Helsinki, Finland.
概括
患有神经认知障碍的人,包括退行性神经认知障碍 (DND),与酒精有关的神经认知障碍 (ARND) 和创伤性脑损伤 (TBIs),与普通人群相比,面临着更高的自杀风险. 这种风险在诊断后的十多年内仍然存在,暴力方法是最常见的.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 神经精神病症状与主要神经认知障碍中的自杀倾向密切相关.
- 了解特定神经认知障碍人群中自杀风险对于有针对性的干预至关重要.
研究的目的:
- 为了调查和比较被诊断患有退行性神经认知障碍 (DNDs),与酒精有关的神经认知障碍 (ARNDs) 和创伤性脑损伤 (TBIs) 的患者中自杀率.
- 评估这些患者群体的长期自杀风险和常见方法,与一般人群相比.
主要方法:
- 一项全国性的基于登记的队列研究确定了1998年至2015年期间诊断的231,817名患者.
- 死亡率的随访一直持续到2018年12月31日.
- 计算了自杀发生率,类型和标准化死亡率 (SMR) 并与一般人群进行了比较.
主要成果:
- 在所有三组中,自杀率都较高:在DND中为0.3%,在ARND中为1.1%,在TBI中为1.0%.
- 与酒精有关的神经认知障碍 (ARNDs) 显示了最高的自杀率 (98.8每10万人年),其次是创伤性脑损伤 (TBIs) (82.0每10万).
- 标准化死亡率 (SMRs) 在所有群体中都明显高于一般人群,DNDs为3.69,ARNDs为2.99,TBIs为1.31. 吊死和溺水等暴力方法最常见.
结论:
- 与普通人群相比,患有DND,ARND和TBI的个体的自杀率明显高.
- 在这些患者群体中,自杀风险在诊断后持续超过10年.
- 这项研究强调了需要加强针对神经认知障碍人群的自杀预防策略.
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