瘤患者的心周窗手术:长期生存和预后因素的分析
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1Department of Cardiovascular and Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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概括
周心窗形成为患有心周溢血 (PE) 的癌症患者提供了有限的长期生存率. 然而,负细胞病理和早期癌症阶段与此程序后更好的结果有关.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 胸部外科手术 胸部外科手术
背景情况:
- 心周溢血 (PE) 是癌症患者的一个关键并发症,通常是由于恶性传播.
- 周心窗形成是耐火性PE的息性手术选择.
- 长期生存和预后因素需要进一步澄清.
研究的目的:
- 评估经过心周窗形成的瘤患者的长期结果和生存率.
- 为了确定影响PE在手术后生存和复发的因素.
- 分析手术方法和细胞病理学发现对患者预后的影响.
主要方法:
- 对166名经过心周窗形成的瘤患者 (2011-2023) 的回顾性分析.
- 数据收集包括癌症类型,手术方法 (迷你胸切除术与胸腔镜),以及细胞病理学结果.
- 考克斯比例风险回归被用来确定生存的独立预后因素.
主要成果:
- 一年整体存活率为31.4%,在50.0个月的中位数随访期间,PE复发16次.
- 胸腔镜术与微型胸腔切除术 (25.6%) 相比,与显著更高的1年生存率 (43.7%) 相关.
- 阴性细胞病理学结果 (45.1%的存活率) 和早期癌症阶段与改善的存活率有关;纽约心脏协会课程,癌症阶段和细胞病理学是独立的预后因素.
结论:
- 在患有PE的癌症患者中,心周窗形成后的长期存活率通常很差.
- 阴性细胞病理或早期瘤阶段的患者表现出更好的生存率.
- 胸腔镜方法和负细胞病理学是这个患者群体的良好预后指标.
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