乙烯氧化物暴露与牙周炎之间的关联:来自NHANES 2013-2014年的横截面研究
Di Miao1,2, Lina Zhao3, Ruoyan Cao4
1Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
BMC public health
|January 16, 2024
概括
对乙烯氧化物 (EO) 的暴露与美国成年人牙周炎风险增加有关. 较高的EO (HbEO) 血红蛋白添加水平与较差的牙周健康相关,这表明存在显著的关联.
科学领域:
- 环境健康 环境健康
- 口腔健康 口腔健康
- 毒理学 毒理学 毒理学
背景情况:
- 已知暴露于乙烯氧化物 (EO) 会引起炎症和氧化应激,这是牙周炎发展的关键因素.
- 欧对牙周健康的具体影响尚不清楚.
- 这项研究调查了美国成年人中EO暴露和牙周炎风险之间的关联.
研究的目的:
- 探索乙烯氧化物 (EO) 暴露与患牙周炎的风险之间的关系.
- 评估特定的EO生物标志物与牙周健康状况之间的关联.
主要方法:
- 利用了2013-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 使用高性能液体染色学-并联质谱法测量了EO (HbEO) 水平的血红蛋白添加物.
- 使用后勤回归分析和子组分析来确定HbEO和牙周炎之间的关联.
主要成果:
- 总共有1497名30岁以上的成年人被分析.
- 在HbEO水平和牙周炎之间发现了积极的非线性关联.
- 在最高HbEO三位数的人群中,牙周健康状况不佳的几率显著更高 (OR=2.80).
结论:
- 在美国成年人中,高HbEO水平与牙周健康状况不佳有关.
- 研究结果表明,乙烯氧化物暴露与牙周炎风险增加之间存在联系.
- 建议进行进一步的纵向研究,以确认EO对牙周状况的影响.
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