对睡眠问题和抑郁症,双相情绪障碍或注意力缺陷障碍的门诊患者进行跨诊断睡眠干预的疗效:随机对照试验的研究方案
Mette Kragh1, Henny Dyrberg2, Maria Speed2
1Department of Affective Disorders, Aarhus University Hospital Psychiatry, Evald Krogs Gade 13A, 8000, Aarhus C, Denmark. mekrag@rm.dk.
Trials
|January 16, 2024
概括
这项研究评估了心理健康状况和睡眠问题的人的跨诊断性睡眠干预. 该治疗旨在改善双相情感障碍,抑郁症或多动症患者的睡眠质量和整体幸福感.
科学领域:
- 精神病学是一个精神病学.
- 睡眠医学 睡眠医学
- 临床心理学 临床心理学
背景情况:
- 患有精神障碍的患者表现出更高的睡眠问题,包括失眠,昼夜节律障碍和高睡眠症.
- 综合失眠认知行为疗法 (CBT-I) 和慢性治疗的跨诊断方法对各种睡眠问题显示出希望.
- 这项研究调查了对患有并发性睡眠问题和双极性障碍,单极性抑郁症或注意力缺陷障碍的患者进行跨诊断性睡眠干预.
研究的目的:
- 评估跨诊断性睡眠干预措施在患有并发性精神健康和睡眠障碍的患者改善睡眠质量的有效性.
- 评估干预对主观和客观睡眠效率的影响,睡眠开始的延迟,睡眠开始后的唤醒,以及唤醒次数.
- 确定干预对失眠严重程度,福祉,个人恢复,工作能力和睡眠药物消费的影响.
主要方法:
- 一项随机对照试验,涉及88名诊断患有双相情感障碍,严重抑郁症或注意力缺陷障碍并经历各种睡眠问题的门诊患者.
- 参与者被分配到六个会议的跨诊断睡眠治疗组或接受一次睡眠卫生教育的对照组.
- 在整个6周的研究期内,对所有患者使用连续性动图,在基线,第二周和第六周进行评估.
主要成果:
- 主要结果是主观睡眠质量的变化,用匹兹堡睡眠质量指数来衡量.
- 二次结果包括睡眠效率的变化,睡眠开始的延迟,睡眠开始后的觉醒,夜间觉醒的数量,失眠的严重程度,福祉,个人恢复,工作能力和睡眠药物的使用.
- 来自动摄影和睡眠日记的数据将用于评估客观睡眠参数和药物消耗.
结论:
- 该研究将于2022年开始,并将持续到2024年中期,将提供有关跨诊断睡眠干预措施有效性的有价值数据.
- 预计结果将为患有精神障碍和同时出现睡眠问题的个体提供增强治疗选择的开发和实施提供信息.
- 这项研究可能会对精神病患者的睡眠障碍管理产生重大影响.
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