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Updated: Jul 5, 2025

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Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
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多药,潜在不合适的药物和老年住院患者的消化不良:一个多中心队列研究
Shintaro Togashi1,2, Hironori Ohinata3, Taiji Noguchi4,5
1Center for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Wako-shi, Japan.
Annals of geriatric medicine and research
|January 17, 2024
概括
这项研究发现,在患有失消症的老年住院患者中,多药和潜在不合适药物 (PIM) 的高率. 然而,这些药物治疗方案与出院时的吞功能结果没有显著联系.
科学领域:
- 老年病的医生 老年病的医生
- 临床药房 临床药房
- 吞障碍 吞障碍 吞障碍
背景情况:
- 有限的数据存在于多药和潜在的不合适的药物 (PIMs) 在老年住院患者的食障碍.
- 这些药物实践与住院期间吞功能之间的关联尚未得到充分理解.
研究的目的:
- 确定65岁及以上患有失消症的住院患者中多药和PIM的患病率.
- 检查多药和PIM与排放时吞功能的关联.
主要方法:
- 一项19个中心的队列研究包括467名年龄≥65岁的住院患者,患有食障碍 (Food Intake LEVEL Scale [FILS]分数≤8).
- 多药性被定义为≥5种药物;使用2023年更新的酒标准确定了PIM.
- 通用线性回归模型分析了多药/PIMs与出院时的FILS分数之间的关联.
主要成果:
- 这项研究分析了399名参与者 (平均年龄83岁).
- 多药在67.7%的患者中流行,而PIM在56.1%的患者中流行.
- 经过对共变量进行调整后,无论是多药店还是PIM都与出院时的FILS分数没有显著的关联.
结论:
- 高比例的老年住院患者经历过多药和PIM.
- 虽然在这个队列中没有直接与出院时的吞功能相关,但研究结果强调了在这个人群中需要定期进行药物评估的必要性.
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