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Updated: Jul 5, 2025

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在肝细胞癌中,USP11通过调节HIF-1α稳定性来促进糖解

Lijun Qiao1,2,3, Weibin Hu4, Linzhi Li5

  • 1College of Pharmacy, Shenzhen Technology University, Shenzhen, Guangdong, China.

Journal of cellular and molecular medicine
|January 17, 2024
PubMed
概括

乌比基特异蛋白酶11 (USP11) 通过稳定HIF-1α促进肝细胞癌 (HCC) 转移,通过PDK1和LDHA途径增强糖解. 这一发现为HCC治疗提供了新的治疗点.

关键词:
杜比基因酶 乌比基因特异蛋白酶 11葡萄糖溶解是什么肝细胞癌是肝细胞癌.缺氧诱导的转录因子-1αα.瘤进展的进展情况

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