Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Author Correction: Parishin A-loaded mesoporous silica nanoparticles modulate macrophage polarization to attenuate tendinopathy.

NPJ Regenerative medicine·2026
Same author

Endogenous Metal Ion-Enriched Immunostimulating Biomimetic Scaffold Improves In Situ Bone Regeneration.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

An energy metabolism-engaged nanomedicine maintains mitochondrial homeostasis to alleviate cellular ageing.

Nature nanotechnology·2025
Same author

Bacteriorhodopsin-Based pH Sensor for Cell Culture Condition Regulation.

Materials (Basel, Switzerland)·2025
Same author

Eicosapentaenoic acid as an antibiofilm agent disrupts mature biofilms of <i>Candida albicans</i>.

Biofilm·2025
Same author

Nanotherapy for Neural Retinal Regeneration.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

相关实验视频

Updated: Jun 29, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.4K

一种基于光敏感蛋白质的可穿戴pH生物计.

Wenxue Li1,2, Siyuan Chen3, Shiwang Xie2

  • 1School of Chemistry and Chemical Engineering, Guangxi University, Nanning, 530004, China.

Journal of materials chemistry. B
|January 17, 2024
PubMed
概括

这项研究引入了一种可穿戴生物传感器,使用细菌原素 (bR) 来通过监测pH水平来检测伤口感染. 基于bR的设备显示了光伏比率和pH之间的可靠线性关系,使得可以准确监测感染.

更多相关视频

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors
09:15

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors

Published on: November 22, 2016

10.6K
Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

2.6K

相关实验视频

Last Updated: Jun 29, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.4K
Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors
09:15

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors

Published on: November 22, 2016

10.6K
Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

2.6K

科学领域:

  • 生物物理学的生物物理.
  • 生物医学工程 生物医学工程
  • 生物传感器技术技术

背景情况:

  • 细菌原素 (bR) 是一种光敏感蛋白质,可将光转化为电信号,因此适用于生物传感器应用.
  • 监测pH值变化对于评估伤口感染状况至关重要.
  • 现有的伤口pH值监测方法可能具有侵入性或缺乏实时功能.

研究的目的:

  • 开发和验证基于bacteriorhodopsin的可穿戴pH生物计,用于监测伤口感染.
  • 为了研究bR电极对pH值敏感的光电特性.
  • 在伤口愈合的背景下,确定光伏信号和pH值变化之间的相关性.

主要方法:

  • 制造一个可穿戴的生物计,使用背后的hodopsin电极.
  • 描述光伏发电和bR电极的pH依赖反应.
  • 确定负光伏与正光伏 (Vn/Vp) 和pH的比率之间的线性关系.
  • 在实验室验证使用老鼠伤口感染模型来评估实时pH监测.

主要成果:

  • bR电极表现出pH敏感的光电效应,在光和黑暗下产生明显的光伏.
  • 在Vn/Vp比率和4.0-10.0.0范围内的pH之间观察到强烈的线性相关性 (R2 = 0.9911).
  • 实验室内实验表明,生物计能够准确地跟踪与大鼠模型中的伤口感染相关的pH值波动.

结论:

  • 一种基于bacteriorhodopsin的新型可穿戴pH生物计已成功开发用于伤口感染监测.
  • 该设备利用了bR的pH依赖光电特性,用于敏感和可靠的pH检测.
  • 这项技术提供了一个有前途的非侵入性工具,用于实时评估伤口状况和感染进展.