最初的椎脊髓脱线性病变与多发性硬化症患者的不安腿综合征没有关联
Neslihan Eskut1, Asli Koskderelioglu1, Muhtesem Gedizlioglu2
1Department of Neurology, University of Health Sciences, Izmir Bozyaka Education and Research Hospital, Izmir, Turkey.
Annals of Indian Academy of Neurology
|January 17, 2024
概括
不安腿综合征 (RLS) 影响近24%的多发性硬化症 (MS) 患者,恶化疲劳,睡眠和生活质量. 在这项研究中,脊髓损伤与RLS无关.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 生活质量研究 研究 生命质量研究
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病,影响生活质量.
- 不安腿综合征 (RLS) 是一种神经疾病,其特点是迫切需要移动腿部.
- 脊髓硬化症和多发性硬化症之间的关系,特别是脊髓损伤,需要进一步研究.
研究的目的:
- 确定患有多发性硬化症 (MS) 患者不安腿综合征 (RLS) 的患病率和严重程度.
- 调查RSS和脊髓病变,疲劳,生活质量和MS患者睡眠障碍之间的关联.
主要方法:
- 从多发性硬化症门诊招募了222名多发性硬化症患者.
- 评估患者使用贝克的抑郁症库存 (BDI),疲劳严重程度量表 (FSS),爱普沃思睡眠度量表 (ESS),匹兹堡睡眠质量指数 (PSQI) 和MS生活质量-54 (MSQoL-54).
- 审查了初始的椎脊髓磁共振成像 (MRI) 对于脱髓化病变.
主要成果:
- 在23.87%的MS患者中,RLS被诊断为MS.
- RLS与睡眠质量差,生活质量降低,疲劳增加和抑郁情绪显著相关.
- 在脊髓脱髓化病变的存在或数量与RLS并发症或严重程度之间没有发现显著的相关性.
结论:
- 同病性RSS会对MS患者的疲劳,睡眠质量,情绪和生活质量产生负面影响.
- 最初的脊髓病变似乎与MS的RLS并发症无关.
- 在这种多发性硬化队列中,RLS症状严重程度与睡眠和身体健康状况不佳有关.
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