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Updated: Jul 5, 2025

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Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
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新Xpert Ultra用于肺外结核的诊断有效性,使用培养和复合参考标准
Jyoti Chaudhary1, Divjot Singh Chawla1, Veenu Gupta1
1Department of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
International journal of applied & basic medical research
|January 17, 2024
概括
艾克斯珀特超级测试显示出诊断肺外结核 (EPTB) 的高灵敏度,检测了150例结核病例中的141. 然而,需要仔细解释痕迹结果,以避免EPTB诊断中出现错误阳性.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 诊断 诊断 诊断 诊断
背景情况:
- 肺外结核 (EPTB) 的诊断仍然具有挑战性.
- 艾克斯珀特超级测定为结核病 (TB) 检测提供了增强的灵敏度,包括一个微量阳性结果的类别.
研究的目的:
- 为了评估EPTB的Xpert Ultra试验的诊断准确性,使用培养和复合参考标准 (CRS) 作为黄金标准.
主要方法:
- 一项前性观察性研究在一年内进行.
- 疑似EPTB患者的样本进行了Ziehl-Neelsen染色,培养和Xpert Ultra测试.
- 诊断准确度指标是通过比较Xpert Ultra结果与培养和CRS进行计算的.
主要成果:
- 在1720名疑似患者中,223人被通过CRS标准诊断出结核病.
- 在150例微生物学确诊的结核病例中,Xpert Ultra检测到141例,显示出高灵敏度.
- 与CRS相比,该测定显示了86.57%的灵敏度和94.98%的特异性,35个痕迹结果,包括6个错误阳性.
结论:
- 由于其高灵敏度,Xpert Ultra可能有助于早期发现EPTB.
- 微量阳性结果的存在需要仔细解释,以排除假阳性.
- 建议进行进一步的研究,以完善对EPTB诊断的Xpert Ultra痕迹结果的解释.
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