肝细胞癌的皮肤表现 肝细胞癌的皮肤表现. 一个系统性审查和元分析
Laith Al-Showbaki1, Ahmad A Toubasi2, Dunia Z Jaber2
1Division of Hematology and Medical Oncology, Department of Medicine, Jordan University Hospital and School of Medicine, the University of Jordan, Amman, Jordan.
Journal of Cancer
|January 17, 2024
概括
肝细胞癌 (HCC) 中的瘤性皮肤疾病在晚期疾病中更为常见. 一些皮肤问题,如皮病轮,表明更好的预后,而皮肤肌炎表明HCC患者的前景较差.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 有限的数据存在于肝细胞癌 (HCC) 中神经瘤皮肤表现的临床意义.
- 了解这些关联对于患者的预后和管理至关重要.
研究的目的:
- 系统地审查和分析HCC中神经瘤皮肤表现的临床意义.
- 评估特定皮肤疾病与患者存活率和治疗反应之间的关联.
主要方法:
- 在2022年12月,对MEDLINE进行了系统的文献搜索.
- 研究包括患有HCC和神经瘤皮肤表现的患者.
- 评估的结果是生存率和针对癌症和针对皮肤的治疗的反应.
主要成果:
- 分析了48项涉及60名HCC患者的研究.
- 常见的表现包括皮肤肌炎,旋转性皮病和.
- 旋转性皮病与较低的死亡风险有关 (OR:0.05),而皮肤肌炎则显示出更高的风险 (OR:3.37).
- 在转移性疾病患者中,皮肤变化更频繁.
- 大多数患者在癌症治疗后的皮肤状况有所改善.
结论:
- 在HCC中,瘤性皮肤表现在患有晚期疾病和转移的患者中更为普遍.
- 特定的皮肤疾病对HCC患者具有重大预后影响.
- 针对癌症的治疗往往会导致相关皮肤异常的改善.
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