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Meng Wang1, Meng-Chan Hao2,3, Yueyue Huangfu1

  • 1College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China.

ACS pharmacology & translational science
|January 17, 2024
PubMed
概括

一种新型的DNA吸附酶抑制剂UHA-2通过向血凝蛋白蛋白来广泛中和多种流感A病毒亚型. 这为开发通用抗病毒抑制剂提供了稳定,高效的战略.

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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