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Updated: Jul 5, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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通过PI3K/AKT通路,YTHDF2调节的马特里林-3通过PI3K/AKT通路缓解了在缺血性中风中发生的输血后的出血转变

Hanze Chen1, Siping Guo2, Runnan Li2

  • 1Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China.

Journal of neuropathology and experimental neurology
|January 17, 2024
PubMed
概括

在缺血性中风模型中,Matrilin-3治疗减轻了出血转变和心脏病发作量. YTH N6-甲基氨酸RNA结合蛋白F2 (YTHDF2) 负调节的母蛋白-3,影响PI3K/AKT通路和血脑屏障的完整性.

关键词:
血液-大脑屏障是什么?输血转化 输血转化缺血性中风是因为缺血性中风.马特里林-3是什么意思在PI3K/AKT信号通路中.YTH N6 - 甲基氨酸RNA结合蛋白F2

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