多域因素与认知的关联在英国生物库研究中
W Y Tan1, C A Hargreaves, N Kandiah
1Dr Saima Hilal, Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, 12 Science Drive 2, #10-03T, Singapore 117549,
The journal of prevention of Alzheimer's disease
|January 17, 2024
概括
不利的生活方式和心理社会因素显著影响老年人的认知功能. 保持健康的习惯和社会联系可以促进老年人群更好的认知和独立.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 痴呆症是一种由血管,生活方式和神经退行性因素影响的复杂综合征.
- 这些因素对老年人认知能力下降的相互作用需要进一步调查.
研究的目的:
- 调查社会人口学,血管,神经成像和生活方式/心理社会因素与老年人认知功能之间的关联.
- 确定这些风险因素领域对认知的综合影响.
主要方法:
- 采用来自英国生物库的数据进行横截面研究.
- 包括19773名60岁及以上的英国居民.
- 通过一般认知能力得分 (g-因子) 评估认知功能;使用多变量线性回归分析关联.
主要成果:
- 较差的认知与年龄较大,女性性别,非白人种族,低教育和社会剥夺有关.
- 肥胖,糖尿病,白质过度强度,久坐,社会隔离和抑郁等不良因素独立地与较差的认知有关.
- 积极因素包括较大的海马体积,最佳睡眠,健康饮食,适度饮酒和电脑使用与更好的认知有关.
结论:
- 不良的生活方式和心理社会因素的结合独立地与老年人的认知功能差异有关.
- 研究结果可以为旨在增强认知健康和保持老年人独立性的公共卫生倡议提供信息.
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