加快处理速度下降的可修改风险因素:来自荷兰三个人口队列的结果
E Jaarsma1, A Nooyens, A A L Kok
1Almar Kok Amsterdam UMC Locatie De Boelelaan: Amsterdam UMC Locatie VUmc, The Netherlands, a.kok1@amsterdamumc.nl.
The journal of prevention of Alzheimer's disease
|January 17, 2024
概括
几种生活方式因素会影响认知处理速度. 吸烟,抑郁症和糖尿病与较低的处理速度和老龄化人口的更快下降有关.
科学领域:
- 神经科学是一个神经科学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 认知能力下降和痴呆风险受生活方式,心血管和心理社会因素的影响.
- 了解可修改的风险因素对于预防认知障碍至关重要.
研究的目的:
- 调查各种可修改风险因素与处理速度下降的独立关联.
- 分析这些关联在三大,以人口为基础的队列中进行长期跟踪.
主要方法:
- 利用了三个荷兰队列研究中的9666名参与者的数据.
- 使用字母数字替换或字母编码任务评估处理速度的下降,以二进制潜伏增长曲线为模型.
- 研究了可修改的风险因素与处理速度下降的水平和速度之间的关联.
主要成果:
- 随着年龄的增长,处理速度的下降加速.
- 吸烟,戒酒和抑郁症状与所有队伍的处理速度降低有关.
- 较高的BMI,糖尿病和过度饮酒与某些队列中的较低处理速度有关.
- 抑郁症状和糖尿病还与更快的处理速度下降率有关.
结论:
- 多种可修改的风险因素与老年人处理速度的水平有关.
- 这些因素的较小子集也会影响认知能力下降的速度.
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