可变性:从头部和部CT和MR图像中OAR轮中观察者间和模式间可变性分析
Gašper Podobnik1, Bulat Ibragimov1,2, Primož Peterlin3
1Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia.
Medical physics
|January 17, 2024
概括
在头癌放射治疗中,风险器官 (OAR) 的轮显示CT和MR图像之间具有相似的变异性,无论观察者的经验如何. 难以围绕的OAR可能会从经验丰富的观察员和遵守指南中受益.
科学领域:
- 辐射疗法 辐射疗法
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 精确的风险器官 (OAR) 轮测定对于放射治疗 (RT) 治疗计划至关重要.
- 磁共振成像为计算机断层扫描 (CT) 提供了补充数据,用于OAR轮,合成CT/MR生成和MR导向RT.
- 在头部和部 (HaN) 区域基于MR的OAR轮的准确性和一致性需要客观评估.
研究的目的:
- 在HaN OAR轮中评估观察者间和模式间的变性.
- 用CT和MR图像来比较初级和高级放射瘤学观察员之间的轮精度.
- 评估图像模式 (CT与MR) 对轮一致性的影响.
主要方法:
- 分析了27名患者的数据集,其中包括CT和MR图像.
- OAR轮是由一名初级观察员 (居民) 和一名高级观察员 (经过董事会认证的瘤学家) 生成的.
- 使用Dice系数 (DC) 和豪斯多夫距离 (HD) 量化了观察者间和模式间的变异性,并评估了MR-CT注册错误.
主要成果:
- 观察者之间的平均变化为69.0% (DC) 和5.1毫米 (HD).
- 平均间接变化率为61.6% (DC) 和6.1毫米 (HD).
- 变化在各种模式中总体上是相似的,在特定的OAR中发现了显著的差异;观察者的经验影响了困难的轮.
结论:
- 在HaN地区的CT和MR模式之间,OAR轮变异性是可比的.
- 观察员的经验并没有显著改变整体轮性能,但对于挑战OAR来说很重要.
- 结果支持使用MR图像用于MR-only和MR-guidedRT,并遵守关键的一致性指南.
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